GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MIR16-1 | increases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in increased expression of MIR16-1 mRNA | PMID:22072212 PMID:22967415 | MIR16-1 | multiple interactions | EXP | | 6480464 | CTD | [Arsenic Trioxide co-treated with MIR15A co-treated with MIR16-1] results in increased cleavage of PARP1 protein; [Arsenic Trioxide co-treated with MIR15A protein co-treated with MIR16-1 protein] results in increased activity of CASP3 protein; [MIR15A protein co-treated with MIR16-1 protein] results in increased susceptibility to Arsenic Trioxide | PMID:21056550 | | ||||||||||||||||||||||
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