GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | multiple interactions | EXP | | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; 3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Colforsin inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Dinoprostone inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Dinoprostone inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] | PMID:12615669 PMID:17586618 PMID:25866079 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of CSF1R protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of IL6 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of CSF1R mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] | PMID:34126350 | TNF | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]] | PMID:31332898 | | ||||||||||||||||||||||
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