GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | multiple interactions | EXP | | 6480464 | CTD | [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Catechin analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Catechin inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Catechin inhibits the reaction [Glucose results in increased expression of TNF protein]; Catechin inhibits the reaction [S100B protein results in increased expression of TNF mRNA]; Catechin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of TNF mRNA] | PMID:17103373 PMID:19557821 PMID:26187476 PMID:29935159 | TNF | decreases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Catechin results in decreased expression of TNF protein | PMID:30445784 PMID:34581093 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Catechin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA]; Catechin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; Catechin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein] | PMID:28533128 PMID:30453148 | TNF | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | Catechin inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]; Catechin inhibits the reaction [Dietary Fats results in increased expression of TNF protein]; Catechin inhibits the reaction [Rotenone results in increased expression of TNF mRNA] | PMID:23365609 PMID:35337893 | |
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