GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Xbp1 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of XBP1 mRNA | PMID:17178593 | Xbp1 | decreases expression | ISO | Xbp1 (Rattus norvegicus) | 6480464 | CTD | Glucose results in decreased expression of XBP1 mRNA | PMID:24349266 | Xbp1 | increases expression | ISO | Xbp1 (Rattus norvegicus) | 6480464 | CTD | Glucose deficiency results in increased expression of XBP1 protein; Glucose results in increased expression of XBP1 mRNA | PMID:21337367 PMID:34801538 | Xbp1 | increases splicing | ISO | XBP1 (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in increased splicing of XBP1 mRNA | PMID:31022492 | Xbp1 | multiple interactions | ISO | Xbp1 (Rattus norvegicus) | 6480464 | CTD | Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of XBP1 mRNA]; Metformin inhibits the reaction [Glucose results in increased expression of XBP1 mRNA] | PMID:34801538 | Xbp1 | multiple interactions | ISO | XBP1 (Homo sapiens) | 6480464 | CTD | 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased splicing of XBP1 mRNA]; XBP1 mRNA alternative form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]] | PMID:31022492 | | ||||||||||||||||||||||
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