GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Xbp1 | increases expression | EXP | | 6480464 | CTD | methylmercuric chloride results in increased expression of XBP1 mRNA alternative form; methylmercuric chloride results in increased expression of XBP1 protein alternative form | PMID:31330229 | Xbp1 | increases splicing | EXP | | 6480464 | CTD | methylmercuric chloride results in increased splicing of XBP1 mRNA | PMID:33454823 | Xbp1 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of XBP1 protein alternative form]; XBP1 protein promotes the reaction [methylmercuric chloride results in decreased expression of CASP12 protein]; XBP1 protein promotes the reaction [methylmercuric chloride results in increased expression of CASP3 protein modified form]; XBP1 protein promotes the reaction [methylmercuric chloride results in increased expression of CASP7 protein modified form] | PMID:31330229 | Xbp1 | increases expression | ISO | XBP1 (Homo sapiens) | 6480464 | CTD | methylmercuric chloride results in increased expression of XBP1 mRNA | PMID:23179753 PMID:27188386 PMID:28001369 | | ||||||||||||||||||||||
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