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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332312
Species: Mus musculus
RGD Object: Gene
Symbol: Xbp1
Name: X-box binding protein 1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xbp1decreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of XBP1 mRNAPMID:35550907
Xbp1increases expressionEXP 6480464CTDDiethylhexyl Phthalate results in increased expression of XBP1 mRNA; Diethylhexyl Phthalate results in increased expression of XBP1 proteinPMID:36583613
Xbp1multiple interactionsEXP 6480464CTDLycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein]PMID:36583613
Xbp1affects expressionISOXbp1 (Rattus norvegicus)6480464CTDDiethylhexyl Phthalate affects the expression of XBP1 protein alternative formPMID:37692514
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