GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SIRT3 | decreases expression | EXP | | 6480464 | CTD | hydroquinone results in decreased expression of SIRT3 mRNA; hydroquinone results in decreased expression of SIRT3 protein | PMID:35302183 | SIRT3 | increases degradation | EXP | | 6480464 | CTD | hydroquinone results in increased degradation of SIRT3 mRNA | PMID:35302183 | SIRT3 | multiple interactions | EXP | | 6480464 | CTD | [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIRT3 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA] | PMID:35302183 | | ||||||||||||||||||||||
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