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GENE - TERM ANNOTATION REPORT

RGD ID: 1315878
Species: Mus musculus
RGD Object: Gene
Symbol: Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Acc ID: GO:0031047
Term: regulatory ncRNA-mediated gene silencing
Definition: A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
Definition Source(s): PMID:15020054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Piwil2involved_inIBAPANTHER:PTN001875625 or ZFIN:ZDB-GENE-030813-2 or TAIR:locus:2007111 or ZFIN:ZDB-GENE-060526-345 or dictyBase:DDB_G0276299 or TAIR:locus:2059370 or WB:WBGene00000106 or FB:FBgn0262739 or MGI:3041167 or WB:WBGene00004323 or UniProtKB:Q9UL18 or UniProtKB:Q9H9G7 or UniProtKB:Q5BD61 or MGI:1930036 or FB:FBgn0087035 or FB:FBgn0000146 or TAIR:locus:2059258 or WB:WBGene00000105 or WB:WBGene00019862 or WB:WBGene00007624 or UniProtKB:Q75HC2 or WB:WBGene00010263 or TAIR:locus:2007760 or MGI:2446632 or WB:WBGene00017641 or FB:FBgn0250816 or UniProtKB:E7EXY4 or WB:WBGene00019971 or PomBase:SPCC736.11 or TAIR:locus:2057851 or UniProtKB:Q9UKV8 or MGI:1928897 or UniProtKB:Q9HCK5 or FB:FBgn00048722290270GO_Central GO_REF:0000033
Piwil2involved_inIMP 2290270UniProt MGI:3709799 PMID:17446352 MGI:3778312 PMID:18381894

MGI:3709799 MGI:3778312 PMID:17446352 PMID:18381894
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