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GENE - TERM ANNOTATION REPORT

RGD ID: 1314223
Species: Mus musculus
RGD Object: Gene
Symbol: Ndufb5
Name: NADH:ubiquinone oxidoreductase subunit B5
Acc ID: GO:0005747
Term: mitochondrial respiratory chain complex I
Definition: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Definition Source(s): GOC:mtg_sensu, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndufb5located_inISONDUFB5 (Homo sapiens)9068941ComplexPortal PMID:28844695

PMID:28844695
Ndufb5part_ofIBAPANTHER:PTN000323600 or UniProtKB:O43674 or UniProtKB:Q02380 or FB:FBgn00114552290270GO_Central GO_REF:0000033
Ndufb5part_ofISOUniProtKB:O436742290270MGI GO_REF:0000119 MGI:4834177
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