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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311541
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp17
Name: matrix metallopeptidase 17
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp17affects expressionEXP 6480464CTDbisphenol A affects the expression of MMP17 mRNAPMID:25181051
Mmp17decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MMP17 mRNAPMID:33296240
Mmp17increases methylationEXP 6480464CTDbisphenol A results in increased methylation of MMP17 genePMID:28505145
Mmp17multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of MMP17 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of MMP17 promoterPMID:23359474 PMID:36041667
Mmp17increases expressionISOMMP17 (Homo sapiens)6480464CTDbisphenol A results in increased expression of MMP17 mRNAPMID:23019147 PMID:34831106
Mmp17increases expressionISOMmp17 (Mus musculus)6480464CTDbisphenol A results in increased expression of MMP17 mRNAPMID:32156529
Mmp17multiple interactionsISOMMP17 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of MMP17 genePMID:31601247
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