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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309952
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mthfr
Name: methylenetetrahydrofolate reductase
Acc ID: CHEBI:15641
Term: 5-methyltetrahydrofolic acid
Definition: A tetrahydrofolic acid that is 5,6,7,8-tetrahydrofolic acid substituted by a methyl group at position 5.
Chemical ID: MESH:C005984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mthfrincreases chemical synthesisISOMTHFR (Homo sapiens)6480464CTDMTHFR protein results in increased chemical synthesis of 5-methyltetrahydrofolatePMID:7647779 PMID:9719624
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