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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309114
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf3r
Name: colony stimulating factor 3 receptor
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf3raffects expressionISOCsf3r (Mus musculus)6480464CTDValproic Acid affects the expression of CSF3R mRNAPMID:17963808
Csf3rincreases expressionISOCSF3R (Homo sapiens)6480464CTDValproic Acid results in increased expression of CSF3R mRNAPMID:23527032
Csf3rincreases methylationISOCSF3R (Homo sapiens)6480464CTDValproic Acid results in increased methylation of CSF3R genePMID:29154799
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