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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcr
Name: BCR activator of RhoGEF and GTPase
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcrmultiple interactionsISOBCR (Homo sapiens)6480464CTDGallic Acid promotes the reaction [Imatinib Mesylate results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]; Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]; Imatinib Mesylate promotes the reaction [Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]]PMID:22245431
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