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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307968
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Elane
Name: elastase, neutrophil expressed
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elanemultiple interactionsISOELANE (Homo sapiens)6480464CTD[Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]PMID:18438818
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