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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307258
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ewsr1
Name: EWS RNA-binding protein 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ewsr1increases expressionEXP 6480464CTDbisphenol A results in increased expression of EWSR1 mRNAPMID:25181051 PMID:34947998
Ewsr1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of EWSR1 genePMID:28505145
Ewsr1decreases expressionISOEWSR1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of EWSR1 mRNAPMID:29275510
Ewsr1decreases expressionISOEwsr1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of EWSR1 mRNAPMID:32156529 PMID:33221593
Ewsr1increases expressionISOEWSR1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of EWSR1 proteinPMID:34186270
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