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GENE - TERM ANNOTATION REPORT

RGD ID: 1304616
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nop2
Name: NOP2 nucleolar protein
Acc ID: GO:0005730
Term: nucleolus
Definition: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nop2located_inISONOP2 (Homo sapiens)1624291RGD PMID:36161484 PMID:8089149

PMID:36161484 PMID:8089149
Nop2located_inISONOP2 (Homo sapiens) or UniProtKB:P46087-1 or UniProtKB:P46087-2 or UniProtKB:P46087-3 or UniProtKB:P46087-41624291RGD GO_REF:0000052
Nop2is_active_inIBAPANTHER:PTN000515974 or SGD:S000005005 or UniProtKB:P46087 or UniProtKB:Q583H81600115GO_CentralGO_REF:0000033

GO_REF:0000033
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