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GENE - TERM ANNOTATION REPORT

RGD ID: 12478367
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Smad2
Name: SMAD family member 2
Acc ID: GO:0007179
Term: transforming growth factor beta receptor signaling pathway
Definition: The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:BHF, GOC:mah, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad2involved_inIEAUniProtKB:Q15796 or UniProtKB:Q62432 or ensembl:ENSMUSP00000130115 or ensembl:ENSP00000262160150520179Ensembl GO_REF:0000107
Smad2acts_upstream_of_or_withinISOMGI:894293 or MGI:98725 or MGI:988349068941MGI PMID:18212064

PMID:18212064
Smad2acts_upstream_of_or_withinISOSmad2 (Mus musculus)9068941MGI PMID:11557747 PMID:14749725

PMID:11557747 PMID:14749725
Smad2involved_inIEAPANTHER:PTHR13703:SF42150520179TreeGrafter GO_REF:0000118
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