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GENE - TERM ANNOTATION REPORT

RGD ID: 12475975
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Notch1
Name: notch receptor 1
Acc ID: PW:0000204
Term: Notch signaling pathway
Definition: The Notch signaling pathway regulates processes involved in early embryonic development. It plays an important role in cell fate determination. Target genes of Notch have been implicated in angiogenesis, somitogenesis and gliogenesis. Deregulation of the Notch signaling pathway underlies a broad spectrum of diseases and clinical conditions.
Definition Source(s): GO:0007219, KEGG:map04330, PID:200015, PubMed:Several articles in PubMed, Reactome:R-HSA-157118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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