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GENE - TERM ANNOTATION REPORT

RGD ID: 12133906
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: PW:0000474
Term: coagulation cascade pathway
Definition: The coagulation cascade is the series of events proceeding via the tissue factor (extrinsic) or the contact activation (intrinsic) pathway and converging in the formation of fibrin clots. Several anticoagulation systems are in place to modulate the pathway. The coagulation cascade and the complement pathway of immune responses are connected in a cross talk.
Definition Source(s): GO:0072378, KEGG:04610, PMID:26018600, PMID:26149013, Reactome:R-HSA-140877
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3 ISOF3 (Homo sapiens)9068941RGD PMID:12787532 PMID:26018600 REF_RGD_ID:11342779 REF_RGD_ID:11352277
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