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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11316
Species: Mus musculus
RGD Object: Gene
Symbol: Slc7a1
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a1affects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of SLC7A1 mRNAPMID:17484886
Slc7a1increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of SLC7A1 mRNAPMID:31919559
Slc7a1increases expressionISOSlc7a1 (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in increased expression of SLC7A1 mRNA; Carbon Tetrachloride results in increased expression of SLC7A1 proteinPMID:17544377 PMID:30723492 PMID:31150632
Slc7a1multiple interactionsISOSlc7a1 (Rattus norvegicus)6480464CTDschizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SLC7A1 mRNA]PMID:31150632
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