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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiaincreases phosphorylationISONFKBIA (Homo sapiens)6480464CTDdecabromobiphenyl ether results in increased phosphorylation of NFKBIA proteinPMID:33675858
Nfkbiamultiple interactionsISONfkbia (Rattus norvegicus)6480464CTDdecabromobiphenyl ether results in increased phosphorylation of and results in increased localization of NFKBIA protein; Melatonin inhibits the reaction [decabromobiphenyl ether results in increased phosphorylation of and results in increased localization of NFKBIA protein]PMID:36566971
Nfkbiamultiple interactionsISONFKBIA (Homo sapiens)6480464CTDLuteolin inhibits the reaction [decabromobiphenyl ether results in increased phosphorylation of NFKBIA protein]PMID:33675858
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