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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiamultiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NFKBIA mRNA; [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of NFKBIA mRNAPMID:34911549
Nfkbiaincreases expressionISONFKBIA (Homo sapiens)6480464CTDOzone results in increased expression of NFKBIA mRNAPMID:23033980 PMID:31476115
Nfkbiaincreases phosphorylationISONfkbia (Rattus norvegicus)6480464CTDOzone results in increased phosphorylation of NFKBIA proteinPMID:33383130
Nfkbiaincreases phosphorylationISONFKBIA (Homo sapiens)6480464CTDOzone results in increased phosphorylation of NFKBIA proteinPMID:23665308
Nfkbiamultiple interactionsISONfkbia (Rattus norvegicus)6480464CTD[Ozone co-treated with Chlorine] affects the expression of NFKBIA mRNAPMID:18636392
Nfkbiamultiple interactionsISONFKBIA (Homo sapiens)6480464CTD[Air Pollutants results in increased abundance of Ozone] which affects the expression of NFKBIA mRNA; [Aripiprazole co-treated with Ozone] results in increased expression of NFKBIA mRNAPMID:31476115 PMID:35430440
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