GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fn1 | increases expression | EXP | | 6480464 | CTD | Folic Acid results in increased expression of FN1 mRNA; Folic Acid results in increased expression of FN1 protein | PMID:29380373 PMID:29789558 PMID:31447676 PMID:34619300 | Fn1 | multiple interactions | EXP | | 6480464 | CTD | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride promotes the reaction [pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of FN1 protein]]; celastrol inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; Metformin inhibits the reaction [Folic Acid results in increased expression of FN1 mRNA]; Metformin inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; pyrazolanthrone inhibits the reaction [Folic Acid results in increased expression of FN1 protein]; SR 144528 inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in increased expression of FN1 protein]] | PMID:29380373 PMID:29789558 PMID:31447676 | Fn1 | increases expression | ISO | FN1 (Homo sapiens) | 6480464 | CTD | Folic Acid results in increased expression of FN1 mRNA | PMID:36354958 | Fn1 | multiple interactions | ISO | FN1 (Homo sapiens) | 6480464 | CTD | Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] | PMID:29380373 | |
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