rosiglitazone (5 mg/kg) (for 23 days) then fasting (for 12 hours)

 sodium chloride solution (for 23 days) then control condition (for 60 days) then fasting (for 12 hours)

 rosiglitazone (10 mg/kg) (for 23 days) then fasting (for 12 hours)

 rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours)

 sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours)

 control condition (between 70 and 77 days)

 rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours)

 sodium chloride solution (for 23 days) then fasting (for 12 hours)

 rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours)

 rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours)