Hsd:SD |
white blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
9.42 |
x 1000 cells/ul |
2.25 |
7.12 |
automated hematology analysis |
|
0 |
|
106016 |
3021 |
Hsd:SD |
blood neutrophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.48 |
x 1000 cells/ul |
0.85 |
2.69 |
automated hematology analysis |
|
0 |
|
106028 |
3021 |
SD-Ahrem2Sage |
blood lymphocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.25 |
x 1000 cells/ul |
1.31 |
4.14 |
automated hematology analysis |
|
0 |
|
106041 |
3021 |
Hsd:SD |
red blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.47 |
x 10E6 cells/ul |
0.21 |
0.66 |
automated hematology analysis |
|
0 |
|
105932 |
3021 |
SD-Ahrem2Sage |
hematocrit |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
43.31 |
% |
1.67 |
5.28 |
automated hematology analysis |
|
0 |
|
105957 |
3021 |
Hsd:SD |
mean corpuscular hemoglobin |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.82 |
pg |
0.44 |
1.39 |
automated hematology analysis |
|
0 |
|
105980 |
3021 |
Hsd:SD |
platelet count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1308.4 |
x 1000 cells/ul |
220.08 |
695.95 |
automated hematology analysis |
|
0 |
|
106004 |
3021 |
SD-Ahrem2Sage |
platelet count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1388.0 |
x 1000 cells/ul |
216.06 |
683.24 |
automated hematology analysis |
|
0 |
|
106005 |
3021 |
BDIX/CrCrl |
mean corpuscular volume |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
erythrocyte size trait |
male |
71 days
| 10 |
47.5 |
fl |
0.03 |
0.1 |
automated hematology analysis |
0.0 |
0 |
MCV, RDW% |
107806 |
3097 |
SD-Ahrem2Sage |
red blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.41 |
x 10E6 cells/ul |
0.36 |
1.14 |
automated hematology analysis |
|
0 |
|
105933 |
3021 |
Hsd:SD |
hematocrit |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
43.31 |
% |
1.49 |
4.71 |
automated hematology analysis |
|
0 |
|
105956 |
3021 |
Hsd:SD |
blood basophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.07 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
|
106076 |
3021 |
Hsd:SD |
mean corpuscular volume |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
57.96 |
fl |
1.26 |
3.98 |
automated hematology analysis |
|
0 |
|
105968 |
3021 |
SD-Ahrem2Sage |
mean corpuscular hemoglobin |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.92 |
pg |
0.39 |
1.23 |
automated hematology analysis |
|
0 |
|
105981 |
3021 |
BDIX/CrCrl |
mean corpuscular volume |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
erythrocyte size trait |
male |
92 days
| 10 |
47.5 |
fl |
0.19 |
0.6 |
automated hematology analysis |
0.0 |
0 |
MCV, RDW% |
107808 |
3097 |
BDIX/CrCrl |
platelet distribution width |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
71 days
| 10 |
8.7 |
fl |
0.16 |
0.5 |
automated hematology analysis |
0.0 |
0 |
|
107882 |
3097 |
BDIX/CrCrl |
platelet distribution width (percentage) |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
71 days
| 10 |
5.2 |
% |
0.0 |
0.0 |
automated hematology analysis |
0.0 |
0 |
|
108146 |
3097 |
BDIX/CrCrl |
platelet distribution width (percentage) |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
92 days
| 10 |
8.5 |
% |
0.0 |
0.0 |
automated hematology analysis |
0.0 |
0 |
|
108148 |
3097 |
SD-Ahrem2Sage |
blood neutrophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.89 |
x 1000 cells/ul |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
|
106029 |
3021 |
Hsd:SD |
blood monocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.29 |
x 1000 cells/ul |
0.14 |
0.44 |
automated hematology analysis |
|
0 |
|
106052 |
3021 |
SD-Ahrem2Sage |
blood eosinophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.18 |
x 1000 cells/ul |
0.18 |
0.57 |
automated hematology analysis |
|
0 |
|
106065 |
3021 |
Hsd:SD |
blood hemoglobin level |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.05 |
g/dl |
0.48 |
1.52 |
automated hematology analysis |
|
0 |
|
105944 |
3021 |
SD-Ahrem2Sage |
mean corpuscular volume |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.44 |
fl |
0.87 |
2.75 |
automated hematology analysis |
|
0 |
|
105969 |
3021 |
Hsd:SD |
mean corpuscular hemoglobin concentration |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.48 |
g/dl |
0.68 |
2.15 |
automated hematology analysis |
|
0 |
|
105992 |
3021 |
SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.37 |
g/dl |
0.7 |
2.21 |
automated hematology analysis |
|
0 |
|
105993 |
3021 |
BDIX/CrCrl |
mean platelet volume |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
71 days
| 10 |
5.9 |
fl |
0.03 |
0.1 |
automated hematology analysis |
0.0 |
0 |
|
107821 |
3097 |
BDIX/CrCrl |
mean platelet volume |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
92 days
| 10 |
5.9 |
fl |
0.06 |
0.2 |
automated hematology analysis |
0.0 |
0 |
|
107823 |
3097 |
BDIX/CrCrl |
red blood cell distribution width-coefficient of variation |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
erythrocyte size trait |
male |
71 days
| 10 |
16.9 |
% |
0.22 |
0.7 |
automated hematology analysis |
0.0 |
0 |
MCV, RDW% |
107846 |
3097 |
BDIX/CrCrl |
platelet distribution width |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
platelet size trait |
male |
92 days
| 10 |
8.6 |
fl |
0.03 |
0.1 |
automated hematology analysis |
0.0 |
0 |
|
107884 |
3097 |
SD-Ahrem2Sage |
white blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.8 |
x 1000 cells/ul |
1.5 |
4.74 |
automated hematology analysis |
|
0 |
|
106017 |
3021 |
SD-Ahrem2Sage |
blood monocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.31 |
x 1000 cells/ul |
0.09 |
0.28 |
automated hematology analysis |
|
0 |
|
106053 |
3021 |
SD-Ahrem2Sage |
blood basophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.02 |
0.06 |
automated hematology analysis |
|
0 |
|
106077 |
3021 |
SD-Ahrem2Sage |
blood hemoglobin level |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.01 |
g/dl |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
|
105945 |
3021 |
BDIX/CrCrl |
red blood cell distribution width-coefficient of variation |
DHD/K12/TRb cells (1.5 X 10E6) then vehicle control condition (1 ml) |
Pica F, etal., Anticancer Drugs. 2012 Jan;23(1):32-42. doi: 10.1097/CAD.0b013e32834a0c8e. |
erythrocyte size trait |
male |
92 days
| 10 |
17.7 |
% |
0.13 |
0.4 |
automated hematology analysis |
0.0 |
0 |
MCV, RDW% |
107848 |
3097 |
Hsd:SD |
blood lymphocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
7.36 |
x 1000 cells/ul |
1.77 |
5.6 |
automated hematology analysis |
|
0 |
|
106040 |
3021 |
Hsd:SD |
blood eosinophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.13 |
x 1000 cells/ul |
0.14 |
0.44 |
automated hematology analysis |
|
0 |
|
106064 |
3021 |