SHR/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
10 |
0.48 |
null |
0.1 |
0.33 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
58110 |
526 |
SHR/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
11 |
0.37 |
null |
0.04 |
0.13 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
58107 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
18 |
12.32 |
ml/min/kg |
0.97 |
4.11 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57595 |
526 |
SHR/NCrl |
FAPGG metabolism-surface area product |
FAPGG (0.6 mmol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
7 |
21.0 |
ml/min/kg |
2.22 |
5.86 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
59634 |
526 |
SHR/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
7 |
1.13 |
null |
0.09 |
0.23 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
57747 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
20 |
13.31 |
ml/min/kg |
0.75 |
3.33 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57794 |
526 |
SHR/NCrl |
FAPGG metabolism-surface area product |
controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
11 |
36.66 |
ml/min/kg |
2.94 |
9.76 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57993 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
9 |
10.29 |
ml/min/kg |
0.74 |
2.23 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
60084 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
8 |
22.26 |
ml/min/kg |
1.77 |
5.01 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
58993 |
526 |
SHR/NCrl |
FAPGG metabolism-surface area product |
FAPGG (0.6 mmol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
9 |
16.24 |
ml/min/kg |
0.96 |
2.87 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
59640 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
18 |
16.03 |
ml/min/kg |
1.14 |
4.85 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57797 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
8 |
9.82 |
ml/min/kg |
0.98 |
2.78 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
60078 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
20 |
10.18 |
ml/min/kg |
0.55 |
2.46 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57592 |
526 |
SHR/NCrl |
FAPGG metabolism-surface area product |
controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77 days-91 days |
10 |
44.72 |
ml/min/kg |
8.86 |
28.03 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
57996 |
526 |
SHR/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
9 |
19.0 |
ml/min/kg |
1.26 |
3.77 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
58999 |
526 |
SHR/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77 days-91 days |
9 |
1.18 |
null |
0.05 |
0.16 |
isolated perfused lung vascular effluent collection |
|
0 |
Moms and pups used in studies were fed Dyets |
57753 |
526 |