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Term:
G protein-coupled receptor activity
(GO:0004930)
Annotations:
Rat: (1950)
Mouse: (754)
Human: (904)
Chinchilla: (236)
Bonobo: (683)
Dog: (1297)
Squirrel: (1129)
Pig: (2004)
Naked Mole-rat: (1035)
Green Monkey: (659)
Parent Terms
Term With Siblings
Child Terms
transmembrane signaling receptor activity
+
acetylcholine receptor activity
+
apolipoprotein A-I receptor activity
axon guidance receptor activity
collagen receptor activity
+
complement receptor activity
+
cytokine receptor activity
+
cytokinin receptor activity
+
death receptor activity
+
G protein-coupled receptor activity
+
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GABA receptor activity
+
glutamate receptor activity
+
hedgehog receptor activity
ICAM-3 receptor activity
immunoglobulin receptor activity
+
latrotoxin receptor activity
mechanoreceptor activity
MHC class I receptor activity
+
MHC class Ib receptor activity
+
MHC class II receptor activity
netrin receptor activity
+
neuregulin receptor activity
neurotensin receptor activity, non-G protein-coupled
non-tyrosine kinase fibroblast growth factor receptor activity
nucleotide receptor activity
+
olfactory receptor activity
+
opsonin receptor activity
+
osmosensor activity
+
reelin receptor activity
semaphorin receptor activity
serotonin receptor activity
+
sulfonylurea receptor activity
taste receptor activity
+
tiggrin receptor activity
transmembrane receptor protein kinase activity
+
transmembrane receptor protein phosphatase activity
+
Wnt receptor activity
bioactive lipid receptor activity
+
cannabinoid receptor activity
choriogonadotropin hormone receptor activity
corticotrophin-releasing factor receptor activity
ecdysis-triggering hormone receptor activity
G protein-coupled adenosine receptor activity
G protein-coupled amine receptor activity
+
G protein-coupled bile acid receptor activity
G protein-coupled chemoattractant receptor activity
+
G protein-coupled chemorepellent receptor activity
G protein-coupled cytokinin receptor activity
G protein-coupled estrogen receptor activity
G protein-coupled folate receptor activity
G protein-coupled GABA receptor activity
G protein-coupled glucose receptor activity
G protein-coupled glutamate receptor activity
+
G protein-coupled neurotransmitter receptor activity
+
G protein-coupled nucleotide receptor activity
G protein-coupled olfactory receptor activity
G protein-coupled opioid receptor activity
+
G protein-coupled peptide receptor activity
+
G protein-coupled photoreceptor activity
G protein-coupled purinergic nucleotide receptor activity
+
G protein-coupled pyrimidinergic nucleotide receptor activity
+
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
+
gastric inhibitory peptide receptor activity
gonadotropin-releasing hormone receptor activity
GPCR taste receptor activity
+
growth hormone secretagogue receptor activity
growth hormone-releasing hormone receptor activity
icosanoid receptor activity
+
luteinizing hormone receptor activity
mast cell secretagogue receptor activity
melanin-concentrating hormone receptor activity
melatonin receptor activity
nicotinic acid receptor activity
parathyroid hormone receptor activity
pheromone receptor activity
+
pituitary adenylate cyclase-activating polypeptide receptor activity
platelet activating factor receptor activity
prosaposin receptor activity
secretin receptor activity
thyroid-stimulating hormone receptor activity
thyrotropin-releasing hormone receptor activity
vasoactive intestinal polypeptide receptor activity
Synonyms
Exact Synonyms:
G protein linked receptor activity ; GPCR activity ; ligand-dependent GPCR activity
Narrow Synonyms:
EBV-induced receptor ; Epstein-Barr Virus-induced receptor activity ; G-protein coupled receptor activity, unknown ligand ; Mas proto-oncogene receptor activity ; RDC1 receptor activity ; SREB receptor ; orphan G protein coupled receptor activity ; orphan GPCR activity ; super conserved receptor expressed in brain receptor activity
Alternate IDs:
GO:0001622 ; GO:0001623 ; GO:0001624 ; GO:0001625 ; GO:0016526
Xrefs:
Reactome:R-HSA-114552 "Thrombin-activated PARs activate G12/13" ; Reactome:R-HSA-114558 "Thrombin-activated PARs activate Gq" ; Reactome:R-HSA-381706 "GLP1R:GLP1 activates G(s)" ; Wikipedia:GPCR ; reactome:R-HSA-167408 "The high affinity receptor complex binds to G-protein"
Definition Sources:
GOC:bf,
http://www.iuphar-db.org
, Wikipedia:GPCR