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Pathways
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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
cell surface pattern recognition receptor signaling pathway +   
cytoplasmic pattern recognition receptor signaling pathway +   
pathogen-associated molecular pattern receptor signaling pathway 
peptidoglycan recognition protein signaling pathway +  
positive regulation of pattern recognition receptor signaling pathway +   
regulation of pattern recognition receptor signaling pathway +   
toll-like receptor signaling pathway +   
The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.

Synonyms
Exact Synonyms: TLR signaling pathway ;   toll-like receptor signalling pathway
Never In Taxon: NCBITaxon:7215 ! Drosophila
Definition Sources: GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447

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