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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:levacetylmethadol pharmacodynamics pathway
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Accession:PW:0002553 term browser browse the term
Definition:The pathway of levacetylmethadol-target interaction and of the biochemical or physiological responses to drug. The drug acts as a mu-receptor agonist. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00677;   levomethadyl acetate pharmacodynamics pathway


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levacetylmethadol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00677 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00677 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00677 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00677 NCBI chr19:38,854,243...38,882,034
Ensembl chr19:47,358,281...47,384,716 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00677 NCBI chr 1:135,504,929...135,540,651
Ensembl chr 1:139,426,556...139,462,393 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00677 NCBI chr 1:144,592,667...144,621,052
Ensembl chr 1:148,314,793...148,342,050 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00677 NCBI chr17:7,681,831...7,688,710
Ensembl chr17:7,669,626...7,673,834 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00677 NCBI chr 3:138,903,371...138,954,915
Ensembl chr 3:146,500,493...146,550,164 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00677 NCBI chr  X:109,633,770...109,654,662
Ensembl chr  X:119,820,695...119,841,598 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00677 NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00677 NCBI chr 3:50,288,926...50,430,152
Ensembl chr 3:51,526,075...51,640,406 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00677 NCBI chr17:18,073,818...18,098,400
Ensembl chr17:18,349,146...18,373,338 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00677 NCBI chr20:59,730,759...59,748,678
Ensembl chr20:61,270,631...61,283,005 		JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00677 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00677 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00677 NCBI chr11:112,654,774...112,666,630
Ensembl chr11:116,587,226...116,595,197 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00677 NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00677 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00677 NCBI chr 9:72,773,866...72,943,790
Ensembl chr 9:100,767,715...100,941,323 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00677 NCBI chr 5:50,045,266...50,049,636
Ensembl chr 5:51,692,416...51,693,684 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00677 NCBI chr 7:112,277,018...112,751,896
Ensembl chr 7:124,966,816...125,437,430 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00677 NCBI chr10:98,428,619...98,446,581
Ensembl chr10:101,899,898...101,918,691 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00677 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00677 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00677 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00677 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00677 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00677 NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00677 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00677 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4069
    drug pathway 395
      nervous system drug pathway 181
        analgesic and/or antipyretic drug pathway 93
          opioid drug pathway 52
            levacetylmethadol drug pathway 30
              levacetylmethadol pharmacodynamics pathway 30
paths to the root