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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:prostacyclin biosynthetic pathway
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Accession:PW:0001534 term browser browse the term
Definition:Those metabolic reactions involved in the biosynthesis of prostacyclin, also known as prostaglandin I2. Prostacyclin and thromboxane play essential roles in cardiovascular system homeostasis.


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prostacyclin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGIS prostaglandin I2 synthase TAS
ISO		 RGD PMID:22679221 PMID:10536678 PMID:10073980 RGD:8552712, RGD:401959739, RGD:401960092 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    classic metabolic pathway 1803
      lipid metabolic pathway 431
        eicosanoid metabolic pathway 18
          prostanoid metabolic pathway 14
            prostacyclin metabolic pathway 1
              prostacyclin biosynthetic pathway 1
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