Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:variegate porphyria pathway
go back to main search page
Accession:PW:0001785 term browser browse the term
Definition:One of several liver porphyrias, all resulting from alterations in the heme biosynthetic pathway. Here, the deficient enzyme is protoporphyrinogen oxidase.
Synonyms:exact_synonym: porphyria variegata disease pathway;   protocoproporphyria pathway;   protoporphyrinogen oxidase deficiency pathway
 related_synonym: SMP:00346


show annotations for term's descendants           Sort by:
variegate porphyria pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate, delta-, dehydratase ISO SMPDB SMP:00346 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 ISO SMPDB SMP:00346 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Blvra biliverdin reductase A ISO SMPDB SMP:00346 NCBI chr 2:126,912,549...126,939,004
Ensembl chr 2:126,912,585...126,939,004 		JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 ISO SMPDB SMP:00346 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294 		JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 ISO SMPDB SMP:00346 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439 		JBrowse link
G Cpox coproporphyrinogen oxidase ISO SMPDB SMP:00346 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase ISO SMPDB SMP:00346 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Ftmt ferritin mitochondrial ISO SMPDB SMP:00346 NCBI chr18:52,464,608...52,466,068
Ensembl chr18:52,464,621...52,466,068 		JBrowse link
G Gusb glucuronidase, beta ISO SMPDB SMP:00346 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890 		JBrowse link
G Hmbs hydroxymethylbilane synthase ISO SMPDB SMP:00346 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Hmox1 heme oxygenase 1 ISO SMPDB SMP:00346 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Ppox protoporphyrinogen oxidase ISO SMPDB SMP:00346 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Urod uroporphyrinogen decarboxylase ISO SMPDB SMP:00346 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase ISO SMPDB SMP:00346 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6070
    disease pathway 2094
      digestive system disease pathway 88
        liver disease pathway 52
          hepatic porphyria pathway 14
            variegate porphyria pathway 14
Path 2
Term Annotations click to browse term
  pathway 6070
    disease pathway 2094
      nutritional and metabolic disease pathway 700
        metabolic disease pathway 659
          inborn error of metabolism pathway 529
            porphyria pathway 14
              hepatic porphyria pathway 14
                variegate porphyria pathway 14
paths to the root