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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:catecholamine biosynthetic pathway
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Accession:PW:0001235 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis of catecholamines. Epinephrine, norepinephrine and dopamine are among the most abundant and are produced primarily from the adrenal medulla and the postganglionic fibers of the sympathetic nervous system.
Synonyms:related_synonym: Catecholamine biosynthesis;   catecholamine biosynthetic process


show annotations for term's descendants           Sort by:
catecholamine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO SMPDB SMP:00012 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase ISO SMPDB SMP:00012 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase ISO SMPDB SMP:00012 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase ISO SMPDB SMP:00012 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 IDA RGD PMID:19903816 RGD:5128868 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
epinephrine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA
ISO		 RGD PMID:7914070 PMID:19342614 RGD:4139902, RGD:4139904 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 IDA RGD PMID:19903816 RGD:5128868 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
norepinephrine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Qdpr quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 IDA RGD PMID:19903816 RGD:5128868 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1854
      biogenic amines and polyamines metabolic pathway 28
        catecholamine metabolic pathway 6
          catecholamine biosynthetic pathway 6
            dopamine biosynthetic pathway 4
            epinephrine biosynthetic pathway 6
            norepinephrine biosynthetic pathway 5
Path 2
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1854
      metabolic pathway pertinent to the brain 131
        neurotransmitter metabolic pathway 34
          amine neurotransmitter metabolic pathway 8
            catecholamine metabolic pathway 6
              catecholamine biosynthetic pathway 6
                dopamine biosynthetic pathway 4
                epinephrine biosynthetic pathway 6
                norepinephrine biosynthetic pathway 5
paths to the root