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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:protein modification pathway via conjugation with ubiquitin and ubiqutin-like molecules
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Accession:PW:0000433 term browser browse the term
Definition:Conjugation of proteins with ubiquitin and ubiquitin-like molecules proceeds via a cascade-like, enzyme-driven mechanism with diverse functionality.


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neddylation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cand1 cullin-associated and neddylation-dissociated 1 ISS RGD PMID:15209382 RGD:1559298 NCBI chr 7:54,681,114...54,719,002
Ensembl chr 7:54,680,900...54,718,993 		JBrowse link
G Cul1 cullin 1 ISS RGD PMID:10772955 RGD:1559274 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980 		JBrowse link
G Cul2 cullin 2 ISS RGD PMID:11818338 RGD:1559275 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cul3 cullin 3 ISS RGD PMID:12781129 RGD:1559280 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cul5 cullin 5 ISS RGD PMID:15021886 RGD:1559277 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Cul7 cullin 7 ISO RGD PMID:15021886 RGD:1559277 NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 ISO RGD PMID:9694792 RGD:41408341 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier ISS RGD PMID:15180522 RGD:1549457 NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 ISS RGD PMID:15209382 RGD:1559298 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694 		JBrowse link
G Rbx1 ring-box 1 ISS RGD PMID:15966899 RGD:1559296 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Uba3 ubiquitin-like modifier activating enzyme 3 IMP RGD PMID:11818503 RGD:634396 NCBI chr 4:129,789,526...129,810,707
Ensembl chr 4:129,789,204...129,810,606 		JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M ISS RGD PMID:15694336 RGD:1559272 NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026 		JBrowse link
sumoylation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pias3 protein inhibitor of activated STAT, 3 IDA RGD PMID:17486098 RGD:1642482 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 IDA RGD PMID:17486098 RGD:1642482 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I IDA RGD PMID:17486098 RGD:1642482 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      pathway pertinent to protein folding, sorting, modification, translocation and degradation 316
        protein modification pathway 15
          protein modification pathway via conjugation with ubiquitin and ubiqutin-like molecules 15
            deubiquitination pathway 0
            neddylation pathway 12
            sumoylation pathway 3
            ubiquitination pathway 0
paths to the root