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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal cell proliferation
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Accession:MP:0000350 term browser browse the term
Definition:anomaly in the ability of a cell population to undergo expansion by cell division


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decreased chondrocyte proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Golgb1 golgin B1 IAGP RGD PMID:21851869 RGD:40902994 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770 		JBrowse link
decreased fibroblast proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:22842522 RGD:7207891 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
decreased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule IMP compared to wild-type RGD PMID:24343121 RGD:13442481 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:24343121 RGD:13442481
increased cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 IDA RGD PMID:12668975 RGD:704417 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:18683040 RGD:4892578 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lpin1m1Hubr lipin 1; ENU induced mutant 1, Hubr IMP compared to Wild type RGD PMID:21715287 RGD:38599010
increased mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:30893315 RGD:126908018 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1bem1Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc IMP RGD PMID:30893315 RGD:126908018
G Cdkn1bem4Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc IMP RGD PMID:30893315 RGD:126908018
increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329 		JBrowse link
G Themism1Adej thymocyte selection associated; mutant1, Adej IAGP compared to BN RGD PMID:22275874 RGD:38599149
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal cell proliferation 25
          abnormal B cell proliferation + 0
          abnormal CD8-positive, alpha-beta memory T cell proliferation + 0
          abnormal Schwann cell proliferation + 0
          abnormal Sertoli cell proliferation + 0
          abnormal T cell proliferation + 10
          abnormal chondrocyte proliferation + 1
          abnormal endothelial cell proliferation + 0
          abnormal enterocyte proliferation 0
          abnormal epidermal stem cell proliferation 0
          abnormal fetal cardiomyocyte proliferation + 0
          abnormal fibroblast proliferation + 1
          abnormal granulosa cell proliferation + 0
          abnormal hematopoietic stem cell proliferation + 0
          abnormal inner cell mass proliferation + 0
          abnormal keratinocyte proliferation + 0
          abnormal kidney cell proliferation + 0
          abnormal lung endothelial cell proliferation + 0
          abnormal macrophage proliferation + 0
          abnormal melanoblast proliferation + 0
          abnormal melanocyte proliferation 0
          abnormal mesenchymal cell proliferation involved in lung development + 0
          abnormal myoblast proliferation + 0
          abnormal neural crest cell proliferation + 0
          abnormal neuron proliferation + 0
          abnormal organ of Corti supporting cell proliferation 0
          abnormal osteoblast proliferation + 0
          abnormal pancreatic beta cell proliferation + 1
          abnormal pancreatic endocrine progenitor cell proliferation + 0
          abnormal primordial germ cell proliferation + 0
          abnormal skeletal muscle satellite cell proliferation + 0
          abnormal small intestinal crypt cell proliferation 0
          abnormal spermatogonia proliferation 0
          abnormal splenocyte proliferation + 1
          abnormal trophectoderm cell proliferation + 0
          abnormal trophoblast giant cell proliferation 0
          abnormal vascular endothelial cell proliferation + 0
          abnormal vascular smooth muscle cell proliferation + 0
          decreased cell proliferation + 6
          increased cell proliferation + 18
paths to the root