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ONTOLOGY REPORT - ANNOTATIONS

Term:IRE1-TRAF2-ASK1 complex
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Accession:GO:1990604 term browser browse the term
Definition:A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
Synonyms:related_synonym: ERN1-TRAF2-ASK1 complex


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IRE1-TRAF2-ASK1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 part_of ISO
IBA		 (PMID:23000344)
GO_REF:0000033		 RGD
GO_Central		 PMID:23000344 GO_REF:0000033 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 part_of ISO
IBA		 (MGI:5616327|PMID:12050113)
GO_REF:0000033		 RGD
GO_Central		 PMID:12050113 GO_REF:0000033 MGI:5616327 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 part_of ISO (PMID:12050113), (PMID:23000344) RGD PMID:12050113 PMID:23000344 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 part_of ISO
ISS		 (PMID:23000344)
GO_REF:0000024
(MGI:5616327|PMID:12050113)		 RGD
ParkinsonsUK-UCL		 PMID:12050113 PMID:23000344 GO_REF:0000024 MGI:5616327 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      endoplasmic reticulum protein-containing complex 152
        IRE1-TRAF2-ASK1 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      organelle 14344
        intracellular organelle 13898
          intracellular membrane-bounded organelle 12331
            endoplasmic reticulum 1933
              endoplasmic reticulum subcompartment 1080
                endoplasmic reticulum membrane 1070
                  IRE1-TRAF2-ASK1 complex 4
paths to the root