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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of retinal ganglion cell axon guidance
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Accession:GO:0090260 term browser browse the term
Definition:Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
Comment:Note that growth cone collapse has been observed only in assays performed in vitro.
Synonyms:related_synonym: axon growth cone collapse



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negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 involved_in ISO
IEA
(PMID:17062560)
GO_REF:0000107
RGD
Ensembl
PMID:17062560 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    locomotion 1439
      negative regulation of locomotion 432
        negative regulation of chemotaxis 67
          negative regulation of axon guidance 1
            negative regulation of retinal ganglion cell axon guidance 1
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            nervous system development 2835
              neurogenesis 2096
                generation of neurons 1808
                  neuron differentiation 1726
                    neuron development 1422
                      neuron projection development 1248
                        neuron projection morphogenesis 768
                          axonogenesis 532
                            axon guidance 275
                              retinal ganglion cell axon guidance 23
                                regulation of retinal ganglion cell axon guidance 3
                                  negative regulation of retinal ganglion cell axon guidance 1
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