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ONTOLOGY REPORT - ANNOTATIONS

Term:receptor antagonist activity
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Accession:GO:0048019 term browser browse the term
Definition:The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
Synonyms:broad_synonym: receptor ligand activity


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receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G DKK2 dickkopf WNT signaling pathway inhibitor 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr32:27,548,877...27,647,039
Ensembl chr32:27,550,833...27,713,838 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664 		JBrowse link
G DKK4 dickkopf WNT signaling pathway inhibitor 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:23,302,124...23,304,824
Ensembl chr16:23,302,320...23,304,834 		JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 enables IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:60,840,804...60,852,821
Ensembl chr 3:60,840,882...60,901,258 		JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:39,934,105...39,937,666
Ensembl chr 6:39,934,068...39,936,628 		JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:26,711,470...26,717,625
Ensembl chr 9:26,711,959...26,716,348 		JBrowse link
activin receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FST follistatin enables IEA Ensembl GO_REF:0000107 NCBI chr 4:61,779,252...61,785,666
Ensembl chr 4:61,779,259...61,783,260 		JBrowse link
G IGSF1 immunoglobulin superfamily member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr  X:102,359,980...102,376,838
Ensembl chr  X:102,359,986...102,377,018 		JBrowse link
chemokine receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 enables ISO (PMID:8631850) BHF-UCL PMID:8631850 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852 		JBrowse link
interleukin-1 receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
interleukin-1 type I receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables ISO (PMID:1828071) BHF-UCL PMID:1828071 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
interleukin-1 type II receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables ISO (PMID:1830582) BHF-UCL PMID:1830582 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18798
    binding 16662
      protein binding 14471
        signaling receptor binding 1513
          receptor antagonist activity 11
            activin receptor antagonist activity 2
            chemokine receptor antagonist activity 1
            fibroblast growth factor receptor antagonist activity 0
            interleukin-1 receptor antagonist activity + 1
paths to the root