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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of complement activation, classical pathway
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Accession:GO:0045959 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:exact_synonym: down regulation of complement activation, classical pathway;   downregulation of complement activation, classical pathway;   negative regulation of complement cascade, classical pathway
 narrow_synonym: inhibition of complement activation, classical pathway


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negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IEA
IBA		 (PMID:22333221)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:22333221 GO_REF:0000033 GO_REF:0000107 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA		 (PMID:22333221)
GO_REF:0000107		 RGD
Ensembl		 PMID:22333221 GO_REF:0000107 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA		 (PMID:9029106)
GO_REF:0000033		 RGD
GO_Central		 PMID:9029106 GO_REF:0000033 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cd46l1 CD46 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:33,996,404...33,997,405
Ensembl chr20:33,996,224...33,997,432 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO
IBA		 (PMID:23482636)
GO_REF:0000033		 RGD
GO_Central		 PMID:23482636 GO_REF:0000033 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750 		JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525 		JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    immune system process 2823
      immune effector process 725
        complement activation 66
          complement activation, classical pathway 41
            negative regulation of complement activation, classical pathway 9
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13308
      regulation of biological process 12905
        regulation of immune system process 1651
          negative regulation of immune system process 565
            negative regulation of immune effector process 142
              negative regulation of leukocyte mediated immunity 79
                negative regulation of lymphocyte mediated immunity 66
                  negative regulation of B cell mediated immunity 16
                    negative regulation of immunoglobulin mediated immune response 16
                      negative regulation of humoral immune response mediated by circulating immunoglobulin 12
                        negative regulation of complement activation, classical pathway 9
paths to the root