Susd4 (sushi domain containing 4)

Gene: Susd4 (sushi domain containing 4) Rattus norvegicus

Analyze

Symbol:

Susd4

Name:

sushi domain containing 4

RGD ID:

1564043

Description:

Predicted to be involved in negative regulation of complement activation, alternative pathway and negative regulation of complement activation, classical pathway. Predicted to be located in membrane. Orthologous to human SUSD4 (sushi domain containing 4); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC289335; RGD1564043; similar to RIKEN cDNA E430021N18; sushi domain-containing protein 4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SUSD4 (sushi domain containing 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Susd4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Susd4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SUSD4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SUSD4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Susd4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SUSD4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SUSD4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Susd4 (sushi domain containing 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MAPKAPK2 (MAPK activated protein kinase 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Susd4 (sushi domain containing 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SUSD4 (sushi domain containing 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	susd4 (sushi domain containing 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	96,982,867 - 97,109,419 (+)	NCBI		GRCr8
mRatBN7.2	13	94,455,180 - 94,577,773 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	94,455,165 - 94,577,750 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	96,960,744 - 97,082,219 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	98,360,678 - 98,482,134 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	95,542,859 - 95,664,303 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	101,181,932 - 101,307,912 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	101,181,994 - 101,307,908 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	106,115,242 - 106,237,600 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	98,831,087 - 98,950,911 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	93,985,798 - 94,106,161 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

bortezomib (ISO)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

clothianidin (ISO)

diarsenic trioxide (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

lead(0) (ISO)

methidathion (ISO)

methoxychlor (EXP)

N-methyl-4-phenylpyridinium (EXP)

O-methyleugenol (ISO)

paracetamol (ISO)

paraquat (EXP)

PCB138 (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of complement activation, alternative pathway (IBA,ISO)

negative regulation of complement activation, classical pathway (IBA,ISO)

regulation of complement activation (ISO)

regulation of postsynaptic neurotransmitter receptor internalization (ISO)

Cellular Component

membrane (IEA)

parallel fiber to Purkinje cell synapse (ISO)

postsynaptic membrane (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23482636

Genomics

Comparative Map Data

Susd4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	96,982,867 - 97,109,419 (+)	NCBI		GRCr8
mRatBN7.2	13	94,455,180 - 94,577,773 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	94,455,165 - 94,577,750 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	96,960,744 - 97,082,219 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	98,360,678 - 98,482,134 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	95,542,859 - 95,664,303 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	101,181,932 - 101,307,912 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	101,181,994 - 101,307,908 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	106,115,242 - 106,237,600 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	98,831,087 - 98,950,911 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	93,985,798 - 94,106,161 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

SUSD4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	223,220,831 - 223,365,235 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	223,220,819 - 223,364,233 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	223,394,173 - 223,537,518 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	221,460,784 - 221,604,167 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	196,613,537 - 196,756,905 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	194,069,335 - 194,212,677 (-)	NCBI		HuRef
CHM1_1	1	224,667,308 - 224,810,684 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	222,458,935 - 222,603,343 (-)	NCBI		T2T-CHM13v2.0

Susd4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	182,591,609 - 182,724,161 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	182,591,425 - 182,724,156 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	182,764,044 - 182,896,596 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	182,763,860 - 182,896,591 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	184,695,037 - 184,825,785 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	184,601,581 - 184,732,329 (+)	NCBI		MGSCv36	mm8
Celera	1	189,807,460 - 189,939,824 (+)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI
cM Map	1	85.94	NCBI

Susd4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955520	1,444,618 - 1,523,260 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955520	1,444,618 - 1,523,214 (+)	NCBI	ChiLan1.0	ChiLan1.0

SUSD4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	25,948,047 - 26,091,295 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	25,904,075 - 26,047,330 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	198,899,771 - 199,043,215 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	203,911,484 - 204,055,677 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	203,911,484 - 204,054,448 (-)	Ensembl	panpan1.1		panPan2

SUSD4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	23,640,882 - 23,685,288 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	23,639,616 - 23,685,304 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	23,666,708 - 23,712,014 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	23,811,029 - 23,857,829 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	23,810,572 - 23,857,853 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	23,554,411 - 23,602,414 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	24,105,361 - 24,152,794 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	24,508,468 - 24,554,928 (+)	NCBI		UU_Cfam_GSD_1.0

Susd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	54,132,032 - 54,258,698 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	485,348 - 615,265 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	488,604 - 615,265 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUSD4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	19,421,565 - 19,551,840 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	19,420,680 - 19,551,941 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	21,915,159 - 22,050,057 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SUSD4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	6,184,878 - 6,327,156 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	6,258,265 - 6,325,793 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	6,415,732 - 6,557,241 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Susd4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	5,531,472 - 5,599,922 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	5,531,507 - 5,600,181 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Susd4
993 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	410
Count of miRNA genes:	229
Interacting mature miRNAs:	275
Transcripts:	ENSRNOT00000052407
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat

Markers in Region

D13Got88

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	94,553,050 - 94,553,248 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	101,283,190 - 101,283,387	NCBI	Rnor6.0
Rnor_5.0	13	106,212,878 - 106,213,075	UniSTS	Rnor5.0
RGSC_v3.4	13	98,927,014 - 98,927,209	RGD	RGSC3.4
RGSC_v3.4	13	98,927,015 - 98,927,212	UniSTS	RGSC3.4
RGSC_v3.1	13	99,115,950 - 99,116,145	RGD
Celera	13	94,082,265 - 94,082,462	UniSTS
RH 3.4 Map	13	641.0	UniSTS
RH 3.4 Map	13	641.0	RGD
RH 2.0 Map	13	699.1	RGD
Cytogenetic Map	13	q26	UniSTS

N28096

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	94,569,930 - 94,570,098 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	101,300,070 - 101,300,237	NCBI	Rnor6.0
Rnor_5.0	13	106,229,758 - 106,229,925	UniSTS	Rnor5.0
RGSC_v3.4	13	98,943,895 - 98,944,062	UniSTS	RGSC3.4
Celera	13	94,099,145 - 94,099,312	UniSTS
Cytogenetic Map	13	q26	UniSTS

RH131207

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	94,577,550 - 94,577,748 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	101,307,690 - 101,307,887	NCBI	Rnor6.0
Rnor_5.0	13	106,237,378 - 106,237,575	UniSTS	Rnor5.0
RGSC_v3.4	13	98,951,515 - 98,951,712	UniSTS	RGSC3.4
Celera	13	94,106,765 - 94,106,962	UniSTS
RH 3.4 Map	13	649.5	UniSTS
Cytogenetic Map	13	q26	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		6							72		22
Low	3	30	24	18	8	18	8	11	2	22	16	11	8
Below cutoff		7	29	19	11	19				13	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000052407 ⟹ ENSRNOP00000045726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	94,455,205 - 94,577,750 (+)	Ensembl
Rnor_6.0 Ensembl	13	101,181,994 - 101,307,908 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103364 ⟹ ENSRNOP00000087687

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	94,455,165 - 94,577,750 (+)	Ensembl

RefSeq Acc Id:

NM_001105982 ⟹ NP_001099452

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	96,987,159 - 97,108,598 (+)	NCBI
mRatBN7.2	13	94,455,488 - 94,576,947 (+)	NCBI
Rnor_6.0	13	101,182,006 - 101,307,086 (+)	NCBI
Rnor_5.0	13	106,115,242 - 106,237,600 (+)	NCBI
RGSC_v3.4	13	98,831,087 - 98,950,911 (+)	RGD
Celera	13	93,985,798 - 94,106,161 (+)	RGD

Sequence:

show sequence

CTCGCTCCTCTGTCTTGCTCGCTCGTTCGCTCGCTCGCTCGCGCAGCGGCGGCAGCAGAGGTCG
CGCACAGATGCGGGTTAGACTGGCGGGGGGAGGAGGCGGAGGAGGGAAGGAAGCTGCATGCATG
AGACCCACAGACTCTTGCAAGCTGGATGCCCTCTGTGGATGAAAGATGTATCATGGAATGAACC
CGAGCAATGGAGATGGATTTCTAGAGCAGCAGCTGCAGCAACAGCAGCCTCAGTCCCCCCAGAG
ACTCTTGGCCGTGATCCTGTGGTTTCAACTGGCGCTGTGCTTTGGCCCTGCGCAGCTCACCGGT
GGGTTCGATGACCTCAACGTGTGTGCTGACCCAGGCGTCCCAGAGAATGGCTTCAGGACCCCCA
GCGGAGGTGTCTTCTTTGAAAGCTCAGTAGCCCGATTTCACTGCCAAGACGGTTTCAAGCTGAA
GGGCTCCTCAAAGAGACTGTGTGTGAAACGCCTCAATGGGACCCTAGGCTGGATCCCAAGTGAC
AAACCTCTCTGCATACAAGAAGACTGCCGGATCCCCCGAATTGAAGATGCTGAGATTCATAACA
AGACATATAGACACGGGGATAAGTTGATCATCAACTGTCATGAGGGATTCAAGATCCGGTACCC
CGACCTGTACAACATGGTTTCGTTATGTCGTGATGATGGGACGTGGGATAACCTGCCCATCTGT
CAAGGCTGCCTGAGACCTCTAGCCTCTTCCAATGGCTACGTGAACATCTCCGAGTTCCAGACCT
CCTTCCCTGTGGGAACTGTGATCGCTTATCGCTGCTTCCCTGGATTTAAACTCGAGGGTTCTGA
GTACCTTGAGTGCTTACACAACCTTATCTGGTCGTCCAGCCCACCCCGGTGCCTTGCTCTGGAA
GTTTGTCCACTACCTCCTATGGTGAGTCACGGAGATTTCATCTGCCACCCGAGGCCTTGTGAGC
GCTACAACCATGGGACTGTGGTGGAATTCTACTGTGATCCCGGCTACAGCCTCACCAGTGACTA
CAAGTACATCACCTGCCAGTATGGAGAGTGGTTTCCTTCCTACCAAGTCTACTGCATCAAATCA
GAACAAACGTGGCCCAGTACCCACGAGACCCTCCTGACCACATGGAAGATCGTGGCATTCACAG
CCACCAGTGTGCTGCTGGTGTTACTGCTCGTCATCCTGGCCAGGATGTTCCAGACCAAGTTCAA
GGCCCACTTCCCCCCCAGGGGTCCTCCCAGGAGTTCCAGCAGTGACCCTGACTTCGTGGTAGTG
GACGGAGTGCCTGTCATGCTCCCGACCTACGATGAGGCTGTGAATGGCAGCTCGAGTGCCTTAG
GCCCCGGGTACCTGGCCTCCGTGGGCCAGGGCTGTCCTTTACCTGTGGATGACCAGAGCCCTCC
AGCCTACCCCGGCTCCGGGGACACGGACACAGGCCCTGGGGAGTCAGAAACCTGTGACAGTACC
TCGGGCTCCTCCGAGATGCTCCAGAGTCTATATTCACCCCCGATGTGCCAAGGGGGCAGCCGCC
CTGCCCCAGACACCCCTGACACGATTTCAAGCACAGCAGGGGAGGTAGCATCCACAAGCCCAGG
CATCGACATTGCAGATGAGATCCCACTCATGGAAGAGGATCCCTAGTCTGGTAACATCCTGCTA
ACCCCACTGTCCCCTTTGGGGGAAAGAGCCTTGAACCTTGGAGAGAGGCCACAGGAGGACAGAG
CTTGGGCACAAGGGGGTGCTTTTAATCTATCTACACGAGGACGGTGATTCATACCACACAACTC
CAGCAGGACTGTGGGTCTGGCCGACAGCAATGGCGGTGCTTTCAAATGAGACTCAAGGGTTTAT
CATGACCTGCAGGGAACAGAGGGCAGAGGGGACTCTCTCAGCCTCACCCCCCATGACAGAGCTG
AGTGTCTCTTGCTACGAAGCGTGAGACAGTGCCACACACATCCTGGCGAGTCACATATCCTGTT
GCTTCTGTTAACAGCAGTCCCTGCTCCTCCAAAAGCATGCCATATTGTATAAATCTGCTTCTAA
ACTCTGCTTTGAACTGTCTAGGGACTTTAGATCTGGACAGGTCGGCATCTGTAAAAAGCCCGTG
TTGACCTGC

hide sequence

RefSeq Acc Id:

XM_039090566 ⟹ XP_038946494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	96,982,867 - 97,109,419 (+)	NCBI
mRatBN7.2	13	94,455,186 - 94,577,773 (+)	NCBI

RefSeq Acc Id:

XM_063272171 ⟹ XP_063128241

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	96,982,867 - 97,109,419 (+)	NCBI

RefSeq Acc Id:

XM_063272172 ⟹ XP_063128242

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	96,982,867 - 97,109,419 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099452	(Get FASTA)	NCBI Sequence Viewer
	XP_038946494	(Get FASTA)	NCBI Sequence Viewer
	XP_063128241	(Get FASTA)	NCBI Sequence Viewer
	XP_063128242	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL94882	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045726
	ENSRNOP00000045726.3
	ENSRNOP00000087687.1

RefSeq Acc Id:

NP_001099452 ⟸ NM_001105982

- UniProtKB:

D4A231 (UniProtKB/TrEMBL), A6JGM6 (UniProtKB/TrEMBL), A0A8I6GG96 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLNVCADPGVPE
NGFRTPSGGVFFESSVARFHCQDGFKLKGSSKRLCVKRLNGTLGWIPSDKPLCIQEDCRIPRIE
DAEIHNKTYRHGDKLIINCHEGFKIRYPDLYNMVSLCRDDGTWDNLPICQGCLRPLASSNGYVN
ISEFQTSFPVGTVIAYRCFPGFKLEGSEYLECLHNLIWSSSPPRCLALEVCPLPPMVSHGDFIC
HPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTW
KIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVN
GSSSALGPGYLASVGQGCPLPVDDQSPPAYPGSGDTDTGPGESETCDSTSGSSEMLQSLYSPPM
CQGGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP

hide sequence

RefSeq Acc Id:

ENSRNOP00000045726 ⟸ ENSRNOT00000052407

RefSeq Acc Id:	XP_038946494 ⟸ XM_039090566
- Peptide Label:	isoform X2
- UniProtKB:	D4A231 (UniProtKB/TrEMBL), A6JGM6 (UniProtKB/TrEMBL), A0A8I6GG96 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000087687 ⟸ ENSRNOT00000103364

RefSeq Acc Id:	XP_063128241 ⟸ XM_063272171
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128242 ⟸ XM_063272172
- Peptide Label:	isoform X1

Protein Domains

Sushi

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A231-F1-model_v2	AlphaFold	D4A231	1-490	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699081

Promoter ID:

EPDNEW_R9606

Type:

single initiation site

Name:

Susd4_1

Description:

sushi domain containing 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	101,182,042 - 101,182,102	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564043	AgrOrtholog
BioCyc Gene	G2FUF-17060	BioCyc
Ensembl Genes	ENSRNOG00000003562	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000052407.6	UniProtKB/TrEMBL
	ENSRNOT00000103364.1	UniProtKB/TrEMBL
Gene3D-CATH	Complement Module, domain 1	UniProtKB/TrEMBL
InterPro	SUSD4	UniProtKB/TrEMBL
	Sushi/SCR/CCP_sf	UniProtKB/TrEMBL
	Sushi_SCR_CCP	UniProtKB/TrEMBL
KEGG Report	rno:289335	UniProtKB/TrEMBL
NCBI Gene	289335	ENTREZGENE
PANTHER	PTHR47007	UniProtKB/TrEMBL
	SUSHI DOMAIN-CONTAINING PROTEIN 4	UniProtKB/TrEMBL
Pfam	Sushi	UniProtKB/TrEMBL
PhenoGen	Susd4	PhenoGen
PROSITE	SUSHI	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003562	RatGTEx
SMART	CCP	UniProtKB/TrEMBL
Superfamily-SCOP	Complement_control_module	UniProtKB/TrEMBL
UniProt	A0A8I6GG96	ENTREZGENE, UniProtKB/TrEMBL
	A6JGM6	ENTREZGENE, UniProtKB/TrEMBL
	D4A231	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Susd4	sushi domain containing 4	RGD1564043_predicted	similar to RIKEN cDNA E430021N18 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1564043_predicted	similar to RIKEN cDNA E430021N18 (predicted)	LOC289335	similar to RIKEN cDNA E430021N18	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC289335	similar to RIKEN cDNA E430021N18			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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