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ONTOLOGY REPORT - ANNOTATIONS


Term:toll-like receptor 5 signaling pathway
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Accession:GO:0034146 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
Synonyms:exact_synonym: TLR5 signaling pathway;   toll-like receptor 5 signalling pathway



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toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) RGD PMID:12447442 MGI:3531416 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4943853|PMID:19912257) RGD PMID:19912257 MGI:4943853 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    immune system process 2823
      activation of immune response 557
        immune response-activating signaling pathway 476
          immune response-activating cell surface receptor signaling pathway 297
            innate immune response activating cell surface receptor signaling pathway 90
              cell surface pattern recognition receptor signaling pathway 77
                cell surface toll-like receptor signaling pathway 72
                  toll-like receptor 5 signaling pathway 3
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    positive regulation of toll-like receptor 5 signaling pathway 0
                    regulation of toll-like receptor 5 signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 19694
    response to stimulus 10517
      response to external stimulus 2701
        response to external biotic stimulus 1825
          response to other organism 1821
            defense response to other organism 1277
              defense response to symbiont 1143
                innate immune response 962
                  regulation of innate immune response 453
                    positive regulation of innate immune response 373
                      activation of innate immune response 302
                        innate immune response-activating signaling pathway 276
                          innate immune response activating cell surface receptor signaling pathway 90
                            cell surface pattern recognition receptor signaling pathway 77
                              cell surface toll-like receptor signaling pathway 72
                                toll-like receptor 5 signaling pathway 3
                                  negative regulation of toll-like receptor 5 signaling pathway 1
                                  positive regulation of toll-like receptor 5 signaling pathway 0
                                  regulation of toll-like receptor 5 signaling pathway + 1
paths to the root