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ONTOLOGY REPORT - ANNOTATIONS


Term:retromer, cargo-selective complex
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Accession:GO:0030906 term browser browse the term
Definition:The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
Synonyms:exact_synonym: cargo-selective retromer subcomplex;   retromer CSC;   retromer complex, inner shell;   retromer, CRC;   retromer, cargo recognition complex


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retromer, cargo-selective complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps26a VPS26, retromer complex component A part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,269,714...9,308,016
Ensembl chrNW_004936521:9,269,287...9,308,153
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G Vps29 VPS29 retromer complex component part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:3,449,993...3,459,008
Ensembl chrNW_004936558:3,449,613...3,459,358
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G Vps35 VPS35 retromer complex component part_of IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936475:50,476...77,797
Ensembl chrNW_004936475:50,321...78,097
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16770
    protein-containing complex 5554
      membrane protein complex 1227
        retromer, cargo-selective complex 3
Path 2
Term Annotations click to browse term
  cellular_component 16770
    cellular anatomical entity 16681
      membrane 8240
        membrane protein complex 1227
          retromer complex 22
            retromer, cargo-selective complex 3
paths to the root