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ONTOLOGY REPORT - ANNOTATIONS

Term:retromer, cargo-selective complex
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Accession:GO:0030906 term browser browse the term
Definition:The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
Synonyms:exact_synonym: cargo-selective retromer subcomplex;   retromer CSC;   retromer complex, inner shell;   retromer, CRC;   retromer, cargo recognition complex

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retromer, cargo-selective complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps26a VPS26, retromer complex component A part_of ISO (PMID:27385586) ParkinsonsUK-UCL PMID:27385586 NCBI chrNW_004955437:21,911,111...21,944,888
Ensembl chrNW_004955437:21,910,680...21,944,428 		JBrowse link
G Vps29 VPS29 retromer complex component part_of ISO (PMID:27385586) ParkinsonsUK-UCL PMID:27385586 NCBI chrNW_004955482:7,397,123...7,405,593
Ensembl chrNW_004955482:7,397,123...7,405,591 		JBrowse link
G Vps35 VPS35 retromer complex component part_of ISO (PMID:20164305), (PMID:27385586) ParkinsonsUK-UCL PMID:20164305 PMID:27385586 NCBI chrNW_004955448:207,582...240,264
Ensembl chrNW_004955448:204,991...240,160 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12560
    protein-containing complex 4415
      membrane protein complex 879
        retromer, cargo-selective complex 3
Path 2
Term Annotations click to browse term
  cellular_component 12560
    cellular anatomical entity 12404
      membrane 5051
        membrane protein complex 879
          retromer complex 20
            retromer, cargo-selective complex 3
paths to the root