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ONTOLOGY REPORT - ANNOTATIONS


Term:retromer, cargo-selective complex
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Accession:GO:0030906 term browser browse the term
Definition:The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
Synonyms:exact_synonym: cargo-selective retromer subcomplex;   retromer CSC;   retromer complex, inner shell;   retromer, CRC;   retromer, cargo recognition complex



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retromer, cargo-selective complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VPS26A VPS26 retromer complex component A part_of IEA Ensembl GO_REF:0000107 NCBI chr10:65,591,415...65,639,894
Ensembl chr10:68,125,409...68,173,317
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G VPS29 VPS29 retromer complex component part_of IEA Ensembl GO_REF:0000107 NCBI chr12:108,061,372...108,071,994
Ensembl chr12:111,457,609...111,467,826
JBrowse link
G VPS35 VPS35 retromer complex component part_of IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17179
    protein-containing complex 5908
      membrane protein complex 1248
        retromer, cargo-selective complex 3
Path 2
Term Annotations click to browse term
  cellular_component 17179
    cellular anatomical entity 16965
      membrane 8102
        membrane protein complex 1248
          retromer complex 21
            retromer, cargo-selective complex 3
paths to the root