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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-ketoglutarate transmembrane transporter activity
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Accession:GO:0015139 term browser browse the term
Definition:Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
Synonyms:exact_synonym: 2-oxoglutarate transporter activity
 xref: reactome:R-HSA-372480 "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]"


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alpha-ketoglutarate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC13A2 solute carrier family 13 member 2 enables IDA
IBA
IEA		 (PMID:10894787) UniProt
GO_Central
Ensembl		 PMID:10894787 GO_REF:0000033 GO_REF:0000107 NCBI chr17:28,473,644...28,497,781
Ensembl chr17:28,473,293...28,497,781 		JBrowse link
G SLC13A3 solute carrier family 13 member 3 enables IDA (PMID:30635937) UniProt PMID:30635937 NCBI chr20:46,557,828...46,684,485
Ensembl chr20:46,557,823...46,684,467 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 enables IDA (PMID:9950961) UniProt PMID:9950961 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 enables IDA (PMID:11327718) UniProt PMID:11327718 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC25A11 solute carrier family 25 member 11 ISO RGD PMID:12939596 RGD:1299466 NCBI chr17:4,937,130...4,940,046
Ensembl chr17:4,937,130...4,940,053 		JBrowse link
G SLC25A21 solute carrier family 25 member 21 enables TAS
IDA
IMP		 (PMID:11083877)
(PMID:29517768)		 Reactome
FlyBase
UniProt		 PMID:11083877 PMID:29517768 Reactome:R-HSA-372480 NCBI chr14:36,677,921...37,172,606
Ensembl chr14:36,677,921...37,172,606 		JBrowse link
oxoglutarate:malate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A11 solute carrier family 25 member 11 enables TAS
IEA		 (PMID:1457818) PINC
Ensembl		 PMID:1457818 GO_REF:0000107 NCBI chr17:4,937,130...4,940,046
Ensembl chr17:4,937,130...4,940,053 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19488
    transporter activity 1282
      transmembrane transporter activity 1175
        organic anion transmembrane transporter activity 276
          carboxylic acid transmembrane transporter activity 190
            dicarboxylic acid transmembrane transporter activity 32
              alpha-ketoglutarate transmembrane transporter activity 6
                alpha-ketoglutarate:proton symporter activity 0
                oxoglutarate:malate antiporter activity 1
paths to the root