Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:metalloendopeptidase inhibitor activity
go back to main search page
Accession:GO:0008191 term browser browse the term
Definition:Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
Synonyms:narrow_synonym: metalloprotease inhibitor;   metalloproteinase inhibitor


show annotations for term's descendants           Sort by:
metalloendopeptidase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BST2 bone marrow stromal cell antigen 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:16,890,257...16,892,989
Ensembl chr19:17,863,991...17,866,728 		JBrowse link
G FETUB fetuin B enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:183,675,258...183,687,754
Ensembl chr 3:192,142,702...192,154,920 		JBrowse link
G LXN latexin enables IEA Ensembl
UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:155,692,283...155,698,605
Ensembl chr 3:163,743,319...163,749,614 		JBrowse link
G NGF nerve growth factor enables ISO (PMID:20164177) UniProt PMID:20164177 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:35,886,741...35,974,133
Ensembl chr 9:36,699,631...36,774,116 		JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:132,372,283...132,890,168
Ensembl chr 5:138,512,523...138,797,416 		JBrowse link
G SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 enables ISO (PMID:11751414) UniProt PMID:11751414 NCBI chr 4:158,941,142...159,437,078
Ensembl chr 4:171,022,442...171,517,005 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 enables ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:15901773 GO_REF:0000002 GO_REF:0000118 RGD:1598578 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17492
    molecular function regulator activity 1870
      enzyme regulator activity 1171
        enzyme inhibitor activity 339
          peptidase inhibitor activity 140
            endopeptidase inhibitor activity 132
              metalloendopeptidase inhibitor activity 11
paths to the root