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ONTOLOGY REPORT - ANNOTATIONS

Term:glucose:sodium symporter activity
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Accession:GO:0005412 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
Synonyms:xref: MetaCyc:RXN-22596;   Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+";   Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-189208 "SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol";   reactome:R-HSA-429613 "SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol"


show annotations for term's descendants           Sort by:
glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102159834 sodium/glucose cotransporter 1-like enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:49,050,154...49,121,392 JBrowse link
G PRPSAP2 phosphoribosyl pyrophosphate synthetase associated protein 2 enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:60,340,879...60,387,856
Ensembl chr12:60,340,883...60,376,568 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 enables ISO
IEA
ISS
IBA		 RGD
Ensembl
UniProt
TreeGrafter
GO_Central		 PMID:15829715 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1624261 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841 		JBrowse link
G SLC5A10 solute carrier family 5 member 10 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:60,281,883...60,332,141
Ensembl chr12:60,281,885...60,332,141 		JBrowse link
G SLC5A11 solute carrier family 5 member 11 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118
G SLC5A2 solute carrier family 5 member 2 enables ISO
IEA
IBA		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:7493971 PMID:14506074 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1599050 RGD:633997 NCBI chr 3:17,081,138...17,089,422
Ensembl chr 3:17,081,141...17,089,568 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 enables IEA
IBA		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr13:197,688,632...197,723,323
Ensembl chr13:197,711,679...197,718,695 		JBrowse link
G SLC5A4 solute carrier family 5 member 4 enables
NOT|enables		 IDA
ISO
IEA
IBA		 (PMID:8077195)
(PMID:13130073), (PMID:20421923), (PMID:22766068)
(MGI:5428377|PMID:22301059)		 UniProt
UniProt
TreeGrafter
GO_Central		 PMID:8077195 PMID:13130073 PMID:20421923 PMID:22301059 PMID:22766068 GO_REF:0000033 GO_REF:0000118 MGI:5428377 NCBI chr14:48,708,047...48,741,440
Ensembl chr14:48,708,047...48,741,440 		JBrowse link
G SLC5A9 solute carrier family 5 member 9 enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:163,429,244...163,568,542
Ensembl chr 6:163,429,433...163,447,854 		JBrowse link
low-affinity glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A4 solute carrier family 5 member 4 enables IDA (PMID:13130073) UniProt PMID:13130073 NCBI chr14:48,708,047...48,741,440
Ensembl chr14:48,708,047...48,741,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18690
    transporter activity 1206
      transmembrane transporter activity 1115
        carbohydrate transmembrane transporter activity 41
          carbohydrate:monoatomic cation symporter activity 16
            glucose:sodium symporter activity 9
              low-affinity glucose:sodium symporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 18690
    transporter activity 1206
      transmembrane transporter activity 1115
        carbohydrate transmembrane transporter activity 41
          sugar transmembrane transporter activity 30
            monosaccharide transmembrane transporter activity 29
              hexose transmembrane transporter activity 27
                D-glucose transmembrane transporter activity 27
                  glucose transmembrane transporter activity 27
                    glucose:sodium symporter activity 9
                      low-affinity glucose:sodium symporter activity 1
paths to the root