Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:glucokinase activity
go back to main search page
Accession:GO:0004340 term browser browse the term
Definition:Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
Synonyms:related_synonym: ATP:D-glucose 6-phosphotransferase activity;   glucokinase (phosphorylating);   glucose kinase activity
 xref: EC:2.7.1.2;   MetaCyc:GLUCOKIN-RXN;   RHEA:17825;   Reactome:R-HSA-5621888 "Defective HK1 does not phosphorylate Glc to form G6P";   Reactome:R-HSA-5621918 "Defective GCK does not phosphorylate Glc to form G6P";   Reactome:R-HSA-70420 "HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P"


show annotations for term's descendants           Sort by:
glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gck glucokinase enables IDA
ISS
ISO
IEA
IBA		 GO_REF:0000024
PMID:7742312
(PMID:12941786), (PMID:16173921), (PMID:18322640), (PMID:19146401), (PMID:22611063), (PMID:8446612)
PMID:6477520
GO_REF:0000107
MGI:1861929 (MGI:5446093|PMID:22698525), (MGI:6377940|PMID:30146176), (PMID:10713097), (PMID:141272), (PMID:3931624), (PMID:7510884), (PMID:7556622), (PMID:7665557), (PMID:9357804), (PMID:9873043)
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:141272 PMID:3931624 PMID:7510884 PMID:7556622 PMID:7665557 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5446093 MGI:6377940, RGD:1582633, RGD:2301923, RGD:2302790, RGD:2302851, RGD:14695076, RGD:14695079 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Hk1 hexokinase 1 enables IDA
IEA
ISO
IBA		 PMID:13211595
PMID:5871820
GO_REF:0000107
(PMID:18509164)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:18509164 PMID:15574336 PMID:13211595 PMID:5871820 GO_REF:0000033 GO_REF:0000107, RGD:1358232, RGD:14695069, RGD:14695073 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 enables IDA
ISO
IBA		 PMID:5871820
(PMID:29298880)
GO_REF:0000033		 RGD
GO_Central		 PMID:29298880 PMID:5871820 GO_REF:0000033, RGD:14695073 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hk3 hexokinase 3 enables IDA
IBA		 PMID:5871820
GO_REF:0000033		 GO_Central PMID:5871820 GO_REF:0000033, RGD:14695073 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Hkdc1 hexokinase domain containing 1 enables ISO
IBA		 (PMID:30517626)
GO_REF:0000033		 RGD
GO_Central		 PMID:30517626 GO_REF:0000033 NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20488
    catalytic activity 6038
      transferase activity 2398
        transferase activity, transferring phosphorus-containing groups 972
          phosphotransferase activity, alcohol group as acceptor 731
            hexokinase activity 5
              glucokinase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20488
    catalytic activity 6038
      transferase activity 2398
        transferase activity, transferring phosphorus-containing groups 972
          kinase activity 804
            carbohydrate kinase activity 21
              hexokinase activity 5
                glucokinase activity 5
paths to the root