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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of ubiquitin-dependent protein catabolic process
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Accession:GO:2000059 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
Synonyms:narrow_synonym: negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown;   negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism;   negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation;   negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism;   negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism
 related_synonym: negative regulation of protein degradation tagging activity;   negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process


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negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr12:4,095,394...4,274,428
Ensembl chr12:4,095,490...4,272,654 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:16173922), (PMID:18560357)
(PMID:23277542)		 UniProt
MGI		 PMID:16173922 PMID:18560357 PMID:23277542 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within ISO (PMID:23792958) MGI PMID:23792958 NCBI chr10:42,214,127...42,223,986
Ensembl chr10:42,215,120...42,223,906 		JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,475,829...44,478,215
Ensembl chr 6:44,477,030...44,478,160 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)		 UniProt PMID:30683861 MGI:6277293 NCBI chr 9:4,395,501...4,408,302
Ensembl chr 9:4,374,650...4,408,299 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605 		JBrowse link
G RPL23 ribosomal protein L23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:23,397,143...23,403,060
Ensembl chr 9:23,262,282...23,403,054 		JBrowse link
G RPL5 ribosomal protein L5 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 6:56,207,171...56,216,030
Ensembl chr 6:56,207,173...56,215,956 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:2,139,011...2,143,160
Ensembl chr17:2,138,779...2,143,178 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO PMID:17000876 ParkinsonsUK-UCL PMID:17000876 RGD:10047192 NCBI chr21:44,408,467...44,418,160
Ensembl chr21:44,408,474...44,415,739 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:55,693,091...55,764,268
Ensembl chr  X:55,693,194...55,763,683 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,158,850...38,172,689
Ensembl chr27:38,158,834...38,172,071 		JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16601693) Ensembl
MGI		 PMID:16601693 GO_REF:0000107 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,318,730...71,324,743
Ensembl chr 8:71,321,625...71,322,992 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,818,699...22,829,737
Ensembl chr11:22,818,743...22,829,736 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,660,026...34,674,129
Ensembl chr25:34,660,553...34,674,037 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr 6:31,560,940...31,757,100
Ensembl chr 6:31,562,834...31,757,678 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,105,960...16,201,902
Ensembl chr13:16,105,990...16,341,153 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:29,735,380...31,113,859
Ensembl chr20:30,356,572...31,113,859 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within ISO (PMID:24960163) MGI PMID:24960163 NCBI chr23:11,812,268...11,820,426
Ensembl chr23:11,813,550...11,820,420 		JBrowse link
G LOC100687242 heat shock protein HSP 90-beta-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,591,965...7,594,265 JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr30:10,361,871...10,382,780
Ensembl chr30:10,361,909...10,381,376 		JBrowse link
G MTM1 myotubularin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23695157) Ensembl
MGI		 PMID:23695157 GO_REF:0000107 NCBI chr  X:118,820,644...118,917,166
Ensembl chr  X:118,820,494...118,916,368 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:66,544,665...66,565,858
Ensembl chr 2:66,544,677...66,561,560 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within ISO (PMID:21715333) MGI PMID:21715333 NCBI chr25:29,751,805...29,781,806
Ensembl chr25:29,751,848...29,781,300 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,260,381...29,338,345
Ensembl chr13:29,260,373...29,336,623 		JBrowse link
G PTGER1 prostaglandin E receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,156,055...48,159,838
Ensembl chr20:48,157,973...48,159,921 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (MGI:5897550|PMID:21804542) UniProt PMID:21804542 MGI:5897550 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605 		JBrowse link
G RPP21 ribonuclease P/MRP subunit p21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:332,003...333,807
Ensembl chr12:332,079...333,806
Ensembl chr12:332,079...333,806 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in ISO (PMID:27060496) UniProt PMID:27060496 NCBI chr20:19,650,936...19,732,987
Ensembl chr20:19,615,426...19,729,474 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (PMID:17981124) MGI PMID:17981124 NCBI chr27:6,664,750...6,719,257
Ensembl chr27:6,664,818...6,714,479 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16611981) Ensembl
MGI		 PMID:16611981 GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22285184) Ensembl
MGI		 PMID:22285184 GO_REF:0000107 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 2:54,403,908...54,406,857
Ensembl chr 2:54,390,411...54,406,872 		JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:10,686,424...10,804,885
Ensembl chr 9:10,687,293...10,803,963 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31537781) Ensembl
MGI		 PMID:31537781 GO_REF:0000107 NCBI chr 5:15,207,400...15,211,905
Ensembl chr 5:15,207,403...15,211,853 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:6,004,595...6,045,999
Ensembl chr38:6,004,659...6,113,714 		JBrowse link
G USP26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133)
(MGI:5926846|PMID:28839133)		 UniProt PMID:28839133 MGI:5926846 NCBI chr  X:103,869,903...103,930,495
Ensembl chr  X:103,872,397...103,875,171 		JBrowse link
G USP38 ubiquitin specific peptidase 38 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:201,810...238,361
Ensembl chr19:210,388...238,384 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,277,328...33,315,601
Ensembl chr 6:33,277,444...33,314,491 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:33378666) UniProt PMID:33378666 NCBI chr  X:35,522,873...35,676,086 JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr 2:17,504,949...17,588,037 JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (PMID:32558204) MGI PMID:32558204 NCBI chr 5:64,525,929...64,527,654 JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:28,949,732...28,990,455
Ensembl chr 8:28,950,061...28,986,812 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    metabolic process 11016
      negative regulation of metabolic process 3114
        negative regulation of catabolic process 371
          negative regulation of ubiquitin-dependent protein catabolic process 62
            negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 43
Path 2
Term Annotations click to browse term
  biological_process 17925
    biological regulation 12446
      regulation of biological process 12082
        regulation of metabolic process 6413
          regulation of macromolecule metabolic process 5877
            regulation of protein metabolic process 1900
              regulation of proteolysis 414
                negative regulation of proteolysis 148
                  negative regulation of proteolysis involved in protein catabolic process 78
                    negative regulation of ubiquitin-dependent protein catabolic process 62
                      negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 43
paths to the root