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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of DNA damage checkpoint
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Accession:GO:2000001 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.
Synonyms:related_synonym: regulation of DNA damage response, signal transduction resulting in cell cycle arrest


show annotations for term's descendants           Sort by:
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5567851|PMID:24489120)		 UniProt
RGD		 PMID:24489120 GO_REF:0000024 MGI:5567851 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO MGI:3851025 (PMID:19481525) RGD PMID:19481525 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO
IBA		 (PMID:27723717), (PMID:27723720)
GO_REF:0000033		 RGD
GO_Central		 PMID:27723717 PMID:27723720 GO_REF:0000033 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104 		JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO MGI:5301830 (PMID:21911473) RGD PMID:21911473 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Fem1b fem-1 homolog B involved_in ISS
ISO		 GO_REF:0000024
(PMID:19330022)		 UniProt
RGD		 PMID:19330022 GO_REF:0000024 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Nek1 NIMA-related kinase 1 involved_in ISO (MGI:5619475|PMID:18843199) RGD PMID:18843199 MGI:5619475 NCBI chr16:28,998,229...29,125,426
Ensembl chr16:28,998,231...29,117,723 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:21504906) RGD PMID:21504906 NCBI chr19:39,235,883...39,268,479
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4432164 (PMID:22802351)		 Ensembl
RGD		 PMID:22802351 GO_REF:0000107 NCBI chr15:36,541,200...36,592,016
Ensembl chr15:36,541,218...36,584,118 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS		 (PMID:21504906)
GO_REF:0000024		 RGD
UniProt		 PMID:21504906 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Wdr76 WD repeat domain 76 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO UniProtKB:Q15554 (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Tti1 TELO2 interacting protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36724785)		 Ensembl
RGD		 PMID:36724785 GO_REF:0000107 NCBI chr 3:146,639,048...146,682,945
Ensembl chr 3:146,639,054...146,682,847 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) RGD PMID:15342622 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18195
      regulation of cellular process 12354
        regulation of cellular response to stress 510
          regulation of DNA damage checkpoint 16
            negative regulation of DNA damage checkpoint + 3
            positive regulation of DNA damage checkpoint + 3
            regulation of mitotic DNA damage checkpoint + 2
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological process 12902
        regulation of cellular process 12354
          regulation of cell cycle 1067
            regulation of cell cycle process 748
              negative regulation of cell cycle process 314
                negative regulation of cell cycle phase transition 263
                  cell cycle checkpoint signaling 184
                    DNA integrity checkpoint signaling 133
                      DNA damage checkpoint signaling 123
                        regulation of DNA damage checkpoint 16
                          negative regulation of DNA damage checkpoint + 3
                          positive regulation of DNA damage checkpoint + 3
                          regulation of mitotic DNA damage checkpoint + 2
paths to the root