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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Accession:GO:1901030 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
Comment:Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID.
Synonyms:exact_synonym: positive regulation of MOMP;   up regulation of MOMP;   up regulation of mitochondrial outer membrane permeabilization;   upregulation of MOMP;   upregulation of mitochondrial outer membrane permeabilization
 narrow_synonym: activation of MOMP;   activation of mitochondrial outer membrane permeabilization
 broad_synonym: positive regulation of mitochondrial outer membrane permeabilization


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positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within IMP (PMID:19096392) MGI PMID:19096392 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in NAS (MGI:6225541|PMID:27488021) ComplexPortal PMID:27488021 MGI:6225541 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Bok BCL2-related ovarian killer involved_in IDA (MGI:5796067|PMID:26949185) UniProt PMID:26949185 MGI:5796067 NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:75,768,964...75,773,584
Ensembl chr10:75,768,964...75,773,581 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IDA (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IDA (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:124,111,665...124,141,263
Ensembl chr 5:124,111,691...124,143,621 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:112,611,262...112,615,586
Ensembl chr12:112,611,113...112,615,583 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:23,788,820...23,818,729
Ensembl chr17:23,794,818...23,818,461 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    positive regulation of biological process 6869
      positive regulation of transport 1054
        positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 28576
    cellular process 17548
      cellular component organization or biogenesis 6978
        cellular component organization 6765
          organelle organization 3726
            mitochondrion organization 585
              mitochondrial membrane organization 123
                regulation of mitochondrial membrane permeability 65
                  positive regulation of mitochondrial membrane permeability 44
                    mitochondrial outer membrane permeabilization involved in programmed cell death 41
                      positive regulation of mitochondrial membrane permeability involved in apoptotic process 39
                        mitochondrial outer membrane permeabilization 31
                          regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 23
                            positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 9
paths to the root